@article{10.11648/j.ccr.20170103.12,
  author = {Assob Nguedia Jules Clement and Verla Sissy Vincent and Nsagha Dickson Shey and Bongkem Edward Afoni and Ngowe Ngowe Marcelin},
  title = {A Cross-Sectional Study on the Evaluation of the Lipid Profile of Regular Blood Donors in the Buea Regional Hospital, Cameroon},
  journal = {Cardiology and Cardiovascular Research},
  volume = {1},
  number = {3},
  pages = {76-83},
  doi = {10.11648/j.ccr.20170103.12},
  url = {https://doi.org/10.11648/j.ccr.20170103.12},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ccr.20170103.12},
  abstract = {There is an acute shortage of blood in most blood banks worldwide to meet up with demands for several medical interventions. A few reports have associated regular blood donation to the lowering of lipid profile parameters. Estimating the lipid profile is a conventional method of assessing an individual’s risk for coronary heart disease. The purpose of this study was to evaluate the lipid profile of blood donors as a whole and to determine the effect of regular blood donation on lipid profile. This study was a cross sectional study that involved 146 consented blood donors, 90 of whom were regular blood donors (study group) and 56 irregular blood donors (control group). A volume of 5ml venous blood was drawn from each fasting participant into a dry biochemistry screw capped tube. This was allowed to clot and the serum was used to determine total cholesterol, Low-density lipoprotein, High-density lipoprotein and triglycerides. Their atherogenic indices were also calculated from the values of the lipid profile parameters. The student’s t test was use to compare means of the study group and control group, while linear regression analysis was used to measure amount of change. The mean total cholesterol (173.54 ± 46.28mg/dl), low-density lipoprotein (96.68 ± 39.37mg/dL), triglycerides (79.28 ± 42.95mg/dL) were comparatively lower in the regular blood donors than the irregular donors (174.61 ± 50.57, 98.16 ± 42.71, 79.82 ± 50.07) respectively, even though did not reach statistical significance (P > 0.05). The mean Low/High-density lipoprotein ratio was also lower in the regular donors than in the irregular donors, though not statistically significant (P > 0.05). 2.05% of the population of blood donors had a risky Low/High-density lipoprotein ratio (i.e. ratio ≥ 3.0). Blood donors as a whole may be said to have a reduced risk of developing coronary heart disease as reflected by the low prevalence of risky Low/High-density lipoprotein ratio and this benefit may be enhanced with regular blood donation as reflected by the lower total cholesterol, low-density lipoprotein, and triglyceride levels in regular blood donors.},
 year = {2017}
}

Copy | Download

TY  - JOUR
T1  - A Cross-Sectional Study on the Evaluation of the Lipid Profile of Regular Blood Donors in the Buea Regional Hospital, Cameroon
AU  - Assob Nguedia Jules Clement
AU  - Verla Sissy Vincent
AU  - Nsagha Dickson Shey
AU  - Bongkem Edward Afoni
AU  - Ngowe Ngowe Marcelin
Y1  - 2017/07/21
PY  - 2017
N1  - https://doi.org/10.11648/j.ccr.20170103.12
DO  - 10.11648/j.ccr.20170103.12
T2  - Cardiology and Cardiovascular Research
JF  - Cardiology and Cardiovascular Research
JO  - Cardiology and Cardiovascular Research
SP  - 76
EP  - 83
PB  - Science Publishing Group
SN  - 2578-8914
UR  - https://doi.org/10.11648/j.ccr.20170103.12
AB  - There is an acute shortage of blood in most blood banks worldwide to meet up with demands for several medical interventions. A few reports have associated regular blood donation to the lowering of lipid profile parameters. Estimating the lipid profile is a conventional method of assessing an individual’s risk for coronary heart disease. The purpose of this study was to evaluate the lipid profile of blood donors as a whole and to determine the effect of regular blood donation on lipid profile. This study was a cross sectional study that involved 146 consented blood donors, 90 of whom were regular blood donors (study group) and 56 irregular blood donors (control group). A volume of 5ml venous blood was drawn from each fasting participant into a dry biochemistry screw capped tube. This was allowed to clot and the serum was used to determine total cholesterol, Low-density lipoprotein, High-density lipoprotein and triglycerides. Their atherogenic indices were also calculated from the values of the lipid profile parameters. The student’s t test was use to compare means of the study group and control group, while linear regression analysis was used to measure amount of change. The mean total cholesterol (173.54 ± 46.28mg/dl), low-density lipoprotein (96.68 ± 39.37mg/dL), triglycerides (79.28 ± 42.95mg/dL) were comparatively lower in the regular blood donors than the irregular donors (174.61 ± 50.57, 98.16 ± 42.71, 79.82 ± 50.07) respectively, even though did not reach statistical significance (P > 0.05). The mean Low/High-density lipoprotein ratio was also lower in the regular donors than in the irregular donors, though not statistically significant (P > 0.05). 2.05% of the population of blood donors had a risky Low/High-density lipoprotein ratio (i.e. ratio ≥ 3.0). Blood donors as a whole may be said to have a reduced risk of developing coronary heart disease as reflected by the low prevalence of risky Low/High-density lipoprotein ratio and this benefit may be enhanced with regular blood donation as reflected by the lower total cholesterol, low-density lipoprotein, and triglyceride levels in regular blood donors.
VL  - 1
IS  - 3
ER  - 

Copy | Download