Safety and Efficacy of Angio-embolization for Complex Renal Cell Carcinoma and Angiomyolipoma: Experience and Results in 20 Patients

Ahmed Mohamed Moeen; Mohamed Abdel Basir Sayed; Amro Farouk Mourad; Tarek El-Diasty; Mohamed M. El-Barody

doi:doi:10.11648/j.ijcu.20220601.23

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Safety and Efficacy of Angio-embolization for Complex Renal Cell Carcinoma and Angiomyolipoma: Experience and Results in 20 Patients

Ahmed Mohamed Moeen, Mohamed Abdel Basir Sayed, Amro Farouk Mourad, Tarek El-Diasty, Mohamed M. El-Barody

Published in International Journal of Clinical Urology (Volume 6, Issue 1)

Received: 12 April 2022 Accepted: 7 May 2022 Published: 24 May 2022

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Abstract

Objective: To evaluate the efficacy and safety of renal artery embolization in treatment of complex angiomyolipoma and renal cell carcinoma. Patients and Methods: Twenty patients were included in this study, 11 patients with primary renal cell carcinoma and 9 patients with AML. These patients were examined by US, CT or and MRI before RAE to evaluate size of the tumor, assess extension of renal cell carcinoma, exclude distant metastasis and assess the complications of angiomyolipoma. Renal artery embolization yield, complications and the impact of patient`s management were analyzed. Results: This study included 20 patients (12 males and 8 females). The age range was 17-75 (47.8±15.5) years. The type of renal masses were renal cell carcinoma in 11 patients and angiomyolipoma in 9 patients (5 bilateral and 4 unilateral). According to the modified Clavien system, 4 patients developed Grade I complication (3 patients developed flank pain (15%) treated with oral analgesics and 1 patient (5%) developed self-limiting perinephric hematoma which resolved spontaneously under antibiotic coverage. Conclusion: RAE is a safe, effective and well tolerated treatment of AML either if large sized which is liable to rupture or symptomatic to stop bleeding. Also, it allows preoperative de-vascularization of RCC to facilitate its surgical resection and as palliative treatment if RCC is un-resectable or metastatic.

Published in	International Journal of Clinical Urology (Volume 6, Issue 1)
DOI	10.11648/j.ijcu.20220601.23
Page(s)	56-62
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2022. Published by Science Publishing Group

Keywords

Renal Artery Embolization, Renal Cell Carcinoma, Angiomyolipoma

References

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Ahmed Mohamed Moeen, Mohamed Abdel Basir Sayed, Amro Farouk Mourad, Tarek El-Diasty, Mohamed M. El-Barody. (2022). Safety and Efficacy of Angio-embolization for Complex Renal Cell Carcinoma and Angiomyolipoma: Experience and Results in 20 Patients. International Journal of Clinical Urology, 6(1), 56-62. https://doi.org/10.11648/j.ijcu.20220601.23

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ACS Style

Ahmed Mohamed Moeen; Mohamed Abdel Basir Sayed; Amro Farouk Mourad; Tarek El-Diasty; Mohamed M. El-Barody. Safety and Efficacy of Angio-embolization for Complex Renal Cell Carcinoma and Angiomyolipoma: Experience and Results in 20 Patients. Int. J. Clin. Urol. 2022, 6(1), 56-62. doi: 10.11648/j.ijcu.20220601.23

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AMA Style

Ahmed Mohamed Moeen, Mohamed Abdel Basir Sayed, Amro Farouk Mourad, Tarek El-Diasty, Mohamed M. El-Barody. Safety and Efficacy of Angio-embolization for Complex Renal Cell Carcinoma and Angiomyolipoma: Experience and Results in 20 Patients. Int J Clin Urol. 2022;6(1):56-62. doi: 10.11648/j.ijcu.20220601.23

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@article{10.11648/j.ijcu.20220601.23,
  author = {Ahmed Mohamed Moeen and Mohamed Abdel Basir Sayed and Amro Farouk Mourad and Tarek El-Diasty and Mohamed M. El-Barody},
  title = {Safety and Efficacy of Angio-embolization for Complex Renal Cell Carcinoma and Angiomyolipoma: Experience and Results in 20 Patients},
  journal = {International Journal of Clinical Urology},
  volume = {6},
  number = {1},
  pages = {56-62},
  doi = {10.11648/j.ijcu.20220601.23},
  url = {https://doi.org/10.11648/j.ijcu.20220601.23},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijcu.20220601.23},
  abstract = {Objective: To evaluate the efficacy and safety of renal artery embolization in treatment of complex angiomyolipoma and renal cell carcinoma. Patients and Methods: Twenty patients were included in this study, 11 patients with primary renal cell carcinoma and 9 patients with AML. These patients were examined by US, CT or and MRI before RAE to evaluate size of the tumor, assess extension of renal cell carcinoma, exclude distant metastasis and assess the complications of angiomyolipoma. Renal artery embolization yield, complications and the impact of patient`s management were analyzed. Results: This study included 20 patients (12 males and 8 females). The age range was 17-75 (47.8±15.5) years. The type of renal masses were renal cell carcinoma in 11 patients and angiomyolipoma in 9 patients (5 bilateral and 4 unilateral). According to the modified Clavien system, 4 patients developed Grade I complication (3 patients developed flank pain (15%) treated with oral analgesics and 1 patient (5%) developed self-limiting perinephric hematoma which resolved spontaneously under antibiotic coverage. Conclusion: RAE is a safe, effective and well tolerated treatment of AML either if large sized which is liable to rupture or symptomatic to stop bleeding. Also, it allows preoperative de-vascularization of RCC to facilitate its surgical resection and as palliative treatment if RCC is un-resectable or metastatic.},
 year = {2022}
}

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TY - JOUR
T1 - Safety and Efficacy of Angio-embolization for Complex Renal Cell Carcinoma and Angiomyolipoma: Experience and Results in 20 Patients
AU - Ahmed Mohamed Moeen
AU - Mohamed Abdel Basir Sayed
AU - Amro Farouk Mourad
AU - Tarek El-Diasty
AU - Mohamed M. El-Barody
Y1 - 2022/05/24
PY - 2022
N1 - https://doi.org/10.11648/j.ijcu.20220601.23
DO - 10.11648/j.ijcu.20220601.23
T2 - International Journal of Clinical Urology
JF - International Journal of Clinical Urology
JO - International Journal of Clinical Urology
SP - 56
EP - 62
PB - Science Publishing Group
SN - 2640-1355
UR - https://doi.org/10.11648/j.ijcu.20220601.23
AB - Objective: To evaluate the efficacy and safety of renal artery embolization in treatment of complex angiomyolipoma and renal cell carcinoma. Patients and Methods: Twenty patients were included in this study, 11 patients with primary renal cell carcinoma and 9 patients with AML. These patients were examined by US, CT or and MRI before RAE to evaluate size of the tumor, assess extension of renal cell carcinoma, exclude distant metastasis and assess the complications of angiomyolipoma. Renal artery embolization yield, complications and the impact of patient`s management were analyzed. Results: This study included 20 patients (12 males and 8 females). The age range was 17-75 (47.8±15.5) years. The type of renal masses were renal cell carcinoma in 11 patients and angiomyolipoma in 9 patients (5 bilateral and 4 unilateral). According to the modified Clavien system, 4 patients developed Grade I complication (3 patients developed flank pain (15%) treated with oral analgesics and 1 patient (5%) developed self-limiting perinephric hematoma which resolved spontaneously under antibiotic coverage. Conclusion: RAE is a safe, effective and well tolerated treatment of AML either if large sized which is liable to rupture or symptomatic to stop bleeding. Also, it allows preoperative de-vascularization of RCC to facilitate its surgical resection and as palliative treatment if RCC is un-resectable or metastatic.
VL - 6
IS - 1
ER -

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Author Information

Ahmed Mohamed Moeen

Department of Urology, Assiut University, Assiut, Egypt
Mohamed Abdel Basir Sayed

Department of Urology, Assiut University, Assiut, Egypt
Amro Farouk Mourad

Department of Radio Diagnosis, South Egypt Cancer Institute, Assiut, Egypt
Tarek El-Diasty

Department of Radio Diagnosis, Urology and Nephrology Center, Mansoura University, Mansoura, Egypt
Mohamed M. El-Barody

Department of Radio Diagnosis, South Egypt Cancer Institute, Assiut, Egypt

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Ahmed Mohamed Moeen, Mohamed Abdel Basir Sayed, Amro Farouk Mourad, Tarek El-Diasty, Mohamed M. El-Barody. (2022). Safety and Efficacy of Angio-embolization for Complex Renal Cell Carcinoma and Angiomyolipoma: Experience and Results in 20 Patients. International Journal of Clinical Urology, 6(1), 56-62. https://doi.org/10.11648/j.ijcu.20220601.23

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ACS Style

Ahmed Mohamed Moeen; Mohamed Abdel Basir Sayed; Amro Farouk Mourad; Tarek El-Diasty; Mohamed M. El-Barody. Safety and Efficacy of Angio-embolization for Complex Renal Cell Carcinoma and Angiomyolipoma: Experience and Results in 20 Patients. Int. J. Clin. Urol. 2022, 6(1), 56-62. doi: 10.11648/j.ijcu.20220601.23

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AMA Style

Ahmed Mohamed Moeen, Mohamed Abdel Basir Sayed, Amro Farouk Mourad, Tarek El-Diasty, Mohamed M. El-Barody. Safety and Efficacy of Angio-embolization for Complex Renal Cell Carcinoma and Angiomyolipoma: Experience and Results in 20 Patients. Int J Clin Urol. 2022;6(1):56-62. doi: 10.11648/j.ijcu.20220601.23

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@article{10.11648/j.ijcu.20220601.23,
  author = {Ahmed Mohamed Moeen and Mohamed Abdel Basir Sayed and Amro Farouk Mourad and Tarek El-Diasty and Mohamed M. El-Barody},
  title = {Safety and Efficacy of Angio-embolization for Complex Renal Cell Carcinoma and Angiomyolipoma: Experience and Results in 20 Patients},
  journal = {International Journal of Clinical Urology},
  volume = {6},
  number = {1},
  pages = {56-62},
  doi = {10.11648/j.ijcu.20220601.23},
  url = {https://doi.org/10.11648/j.ijcu.20220601.23},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijcu.20220601.23},
  abstract = {Objective: To evaluate the efficacy and safety of renal artery embolization in treatment of complex angiomyolipoma and renal cell carcinoma. Patients and Methods: Twenty patients were included in this study, 11 patients with primary renal cell carcinoma and 9 patients with AML. These patients were examined by US, CT or and MRI before RAE to evaluate size of the tumor, assess extension of renal cell carcinoma, exclude distant metastasis and assess the complications of angiomyolipoma. Renal artery embolization yield, complications and the impact of patient`s management were analyzed. Results: This study included 20 patients (12 males and 8 females). The age range was 17-75 (47.8±15.5) years. The type of renal masses were renal cell carcinoma in 11 patients and angiomyolipoma in 9 patients (5 bilateral and 4 unilateral). According to the modified Clavien system, 4 patients developed Grade I complication (3 patients developed flank pain (15%) treated with oral analgesics and 1 patient (5%) developed self-limiting perinephric hematoma which resolved spontaneously under antibiotic coverage. Conclusion: RAE is a safe, effective and well tolerated treatment of AML either if large sized which is liable to rupture or symptomatic to stop bleeding. Also, it allows preoperative de-vascularization of RCC to facilitate its surgical resection and as palliative treatment if RCC is un-resectable or metastatic.},
 year = {2022}
}

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