Evaluation of the Results Obtained from Microbiological Analysis of Blood Cultures over 5 Years

Mine Turhanoglu; Esra Koyuncu; Fulya Bayındır Bilman; Arzu Onur; Fikret Tekay

doi:doi:10.11648/j.jfmhc.20160204.14

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Evaluation of the Results Obtained from Microbiological Analysis of Blood Cultures over 5 Years

Mine Turhanoglu, Esra Koyuncu, Fulya Bayındır Bilman, Arzu Onur, Fikret Tekay

Published in Journal of Family Medicine and Health Care (Volume 2, Issue 4)

Received: 24 August 2016 Accepted: 10 September 2016 Published: 3 November 2016

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Abstract

The infections caused by bacteria that reproduce in blood cultures are important medical problems that cause morbidity and mortality. The infections caused by resistant microorganisms are gradually increasing because of the patient’s long stay in hospital, invasive procedures, and application of multi and parenteral antibiotic treatment. The microorganisms that reproduced in the blood cultures of patients in different cultures between 2010-2015 in Diyarbakır Selahaddin Eyyübi State Hospital and the resistance of these microorganisms to antibiotics were assessed retrospectively. In the study, a total of 196 patients’ blood culture results were examined retrospectively. A total of 66.8% of the growth microorganisms (127) were composed of Gram positive cocci, 26.5% of them (52) were composed of Gram-negative bacilli and 6.7% of them (11) were composed of Candida spp. Among the reproduced microorganisms, coagulase negative staphylococci (CNS) were found to be 52.5% (103), Staphylococcus aureus to be 4.9% (9), Acinetobacter spp to be 7.3% (14), Escherichia coli to be 4.7% (9), Klebsiella spp to be 8.4% (16), Candida spp. to be 6.7% (11), Pseudomonas spp. to be 4.7% (9), Enterococcus faecalis to be 2% (4), Micrococcus luteus to be 2% (4), Kocuria kristinae to be 2.5% (5), Rhizobium radiobacter to be 0.5% (1), Leuconostoc mesenteroides subsp. cremoris to be 1% (1), Sphingomonas paucimobilis 0.5% (1), Pantoea spp. to be 0.5% (1), and Stenotrophomonas maltophilia to be 0.5% (1). The highest rate of resistance was found to be against meropenem, imipenem and ceftazidime in Acinetobacter spp with 80%, against ceftazidime in Klebsiella spp with 73.4%, against imipenem with 75%, against meropenem and ciprofloxacin with 62.5% in Pseudomonas aeruginosa, and against ceftriaxon, cefuroxime and cefuroxime axetil in Escherichia coli with 60%. Penicillin with 100% and tetracycline with 33.3% in S. aureus; penicillin with 97.6% and erythromycin with 82.1% were the antibiotics to which the highest resistance developed. While no resistance was determined against fusidic acid, trimethoprim sulfamethoxazole, linezolid, vancomycin, teicoplanin, and tigecycline in S. aureus, the resistance was not determined only against tigecycline and vancomycin in CNS. Fifty seven % of S. aureus strains and 83.8% of CNS strains were found to be resistant to methicillin. In our study, it is aimed to determine the mostly reproduced bacteria in blood samples as the result of blood circulation infections of patients staying in different clinics and to research their resistance profiles that developed against antibiotics retrospectively.

Published in	Journal of Family Medicine and Health Care (Volume 2, Issue 4)
DOI	10.11648/j.jfmhc.20160204.14
Page(s)	43-50
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2016. Published by Science Publishing Group

Keywords

Blood Cultures, Antibiotic Sensitivity, S. aureus, Coagulase Negative Staphylococcus

References

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APA Style

Mine Turhanoglu, Esra Koyuncu, Fulya Bayındır Bilman, Arzu Onur, Fikret Tekay. (2016). Evaluation of the Results Obtained from Microbiological Analysis of Blood Cultures over 5 Years. Journal of Family Medicine and Health Care, 2(4), 43-50. https://doi.org/10.11648/j.jfmhc.20160204.14

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ACS Style

Mine Turhanoglu; Esra Koyuncu; Fulya Bayındır Bilman; Arzu Onur; Fikret Tekay. Evaluation of the Results Obtained from Microbiological Analysis of Blood Cultures over 5 Years. J. Fam. Med. Health Care 2016, 2(4), 43-50. doi: 10.11648/j.jfmhc.20160204.14

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AMA Style

Mine Turhanoglu, Esra Koyuncu, Fulya Bayındır Bilman, Arzu Onur, Fikret Tekay. Evaluation of the Results Obtained from Microbiological Analysis of Blood Cultures over 5 Years. J Fam Med Health Care. 2016;2(4):43-50. doi: 10.11648/j.jfmhc.20160204.14

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@article{10.11648/j.jfmhc.20160204.14,
  author = {Mine Turhanoglu and Esra Koyuncu and Fulya Bayındır Bilman and Arzu Onur and Fikret Tekay},
  title = {Evaluation of the Results Obtained from Microbiological Analysis of Blood Cultures over 5 Years},
  journal = {Journal of Family Medicine and Health Care},
  volume = {2},
  number = {4},
  pages = {43-50},
  doi = {10.11648/j.jfmhc.20160204.14},
  url = {https://doi.org/10.11648/j.jfmhc.20160204.14},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.jfmhc.20160204.14},
  abstract = {The infections caused by bacteria that reproduce in blood cultures are important medical problems that cause morbidity and mortality. The infections caused by resistant microorganisms are gradually increasing because of the patient’s long stay in hospital, invasive procedures, and application of multi and parenteral antibiotic treatment. The microorganisms that reproduced in the blood cultures of patients in different cultures between 2010-2015 in Diyarbakır Selahaddin Eyyübi State Hospital and the resistance of these microorganisms to antibiotics were assessed retrospectively. In the study, a total of 196 patients’ blood culture results were examined retrospectively. A total of 66.8% of the growth microorganisms (127) were composed of Gram positive cocci, 26.5% of them (52) were composed of Gram-negative bacilli and 6.7% of them (11) were composed of Candida spp. Among the reproduced microorganisms, coagulase negative staphylococci (CNS) were found to be 52.5% (103), Staphylococcus aureus to be 4.9% (9), Acinetobacter spp to be 7.3% (14), Escherichia coli to be 4.7% (9), Klebsiella spp to be 8.4% (16), Candida spp. to be 6.7% (11), Pseudomonas spp. to be 4.7% (9), Enterococcus faecalis to be 2% (4), Micrococcus luteus to be 2% (4), Kocuria kristinae to be 2.5% (5), Rhizobium radiobacter to be 0.5% (1), Leuconostoc mesenteroides subsp. cremoris to be 1% (1), Sphingomonas paucimobilis 0.5% (1), Pantoea spp. to be 0.5% (1), and Stenotrophomonas maltophilia to be 0.5% (1). The highest rate of resistance was found to be against meropenem, imipenem and ceftazidime in Acinetobacter spp with 80%, against ceftazidime in Klebsiella spp with 73.4%, against imipenem with 75%, against meropenem and ciprofloxacin with 62.5% in Pseudomonas aeruginosa, and against ceftriaxon, cefuroxime and cefuroxime axetil in Escherichia coli with 60%. Penicillin with 100% and tetracycline with 33.3% in S. aureus; penicillin with 97.6% and erythromycin with 82.1% were the antibiotics to which the highest resistance developed. While no resistance was determined against fusidic acid, trimethoprim sulfamethoxazole, linezolid, vancomycin, teicoplanin, and tigecycline in S. aureus, the resistance was not determined only against tigecycline and vancomycin in CNS. Fifty seven % of S. aureus strains and 83.8% of CNS strains were found to be resistant to methicillin. In our study, it is aimed to determine the mostly reproduced bacteria in blood samples as the result of blood circulation infections of patients staying in different clinics and to research their resistance profiles that developed against antibiotics retrospectively.},
 year = {2016}
}

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TY - JOUR
T1 - Evaluation of the Results Obtained from Microbiological Analysis of Blood Cultures over 5 Years
AU - Mine Turhanoglu
AU - Esra Koyuncu
AU - Fulya Bayındır Bilman
AU - Arzu Onur
AU - Fikret Tekay
Y1 - 2016/11/03
PY - 2016
N1 - https://doi.org/10.11648/j.jfmhc.20160204.14
DO - 10.11648/j.jfmhc.20160204.14
T2 - Journal of Family Medicine and Health Care
JF - Journal of Family Medicine and Health Care
JO - Journal of Family Medicine and Health Care
SP - 43
EP - 50
PB - Science Publishing Group
SN - 2469-8342
UR - https://doi.org/10.11648/j.jfmhc.20160204.14
AB - The infections caused by bacteria that reproduce in blood cultures are important medical problems that cause morbidity and mortality. The infections caused by resistant microorganisms are gradually increasing because of the patient’s long stay in hospital, invasive procedures, and application of multi and parenteral antibiotic treatment. The microorganisms that reproduced in the blood cultures of patients in different cultures between 2010-2015 in Diyarbakır Selahaddin Eyyübi State Hospital and the resistance of these microorganisms to antibiotics were assessed retrospectively. In the study, a total of 196 patients’ blood culture results were examined retrospectively. A total of 66.8% of the growth microorganisms (127) were composed of Gram positive cocci, 26.5% of them (52) were composed of Gram-negative bacilli and 6.7% of them (11) were composed of Candida spp. Among the reproduced microorganisms, coagulase negative staphylococci (CNS) were found to be 52.5% (103), Staphylococcus aureus to be 4.9% (9), Acinetobacter spp to be 7.3% (14), Escherichia coli to be 4.7% (9), Klebsiella spp to be 8.4% (16), Candida spp. to be 6.7% (11), Pseudomonas spp. to be 4.7% (9), Enterococcus faecalis to be 2% (4), Micrococcus luteus to be 2% (4), Kocuria kristinae to be 2.5% (5), Rhizobium radiobacter to be 0.5% (1), Leuconostoc mesenteroides subsp. cremoris to be 1% (1), Sphingomonas paucimobilis 0.5% (1), Pantoea spp. to be 0.5% (1), and Stenotrophomonas maltophilia to be 0.5% (1). The highest rate of resistance was found to be against meropenem, imipenem and ceftazidime in Acinetobacter spp with 80%, against ceftazidime in Klebsiella spp with 73.4%, against imipenem with 75%, against meropenem and ciprofloxacin with 62.5% in Pseudomonas aeruginosa, and against ceftriaxon, cefuroxime and cefuroxime axetil in Escherichia coli with 60%. Penicillin with 100% and tetracycline with 33.3% in S. aureus; penicillin with 97.6% and erythromycin with 82.1% were the antibiotics to which the highest resistance developed. While no resistance was determined against fusidic acid, trimethoprim sulfamethoxazole, linezolid, vancomycin, teicoplanin, and tigecycline in S. aureus, the resistance was not determined only against tigecycline and vancomycin in CNS. Fifty seven % of S. aureus strains and 83.8% of CNS strains were found to be resistant to methicillin. In our study, it is aimed to determine the mostly reproduced bacteria in blood samples as the result of blood circulation infections of patients staying in different clinics and to research their resistance profiles that developed against antibiotics retrospectively.
VL - 2
IS - 4
ER -

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Author Information

Mine Turhanoglu

Department of Medical Microbiology, Diyarbak?r Selahaddin Eyyübi State Hospital, Diyarbak?r, Turkey
Esra Koyuncu

Department of Medical Microbiology, Diyarbak?r Selahaddin Eyyübi State Hospital, Diyarbak?r, Turkey
Fulya Bayındır Bilman
Arzu Onur

Department of Medical Microbiology, Gazi Ya?argil Training and Research Hospital, Diyarbak?r, Turkey
Fikret Tekay

Department of Medical Microbiology, Diyarbak?r Selahaddin Eyyübi State Hospital, Diyarbak?r, Turkey

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Mine Turhanoglu, Esra Koyuncu, Fulya Bayındır Bilman, Arzu Onur, Fikret Tekay. (2016). Evaluation of the Results Obtained from Microbiological Analysis of Blood Cultures over 5 Years. Journal of Family Medicine and Health Care, 2(4), 43-50. https://doi.org/10.11648/j.jfmhc.20160204.14

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ACS Style

Mine Turhanoglu; Esra Koyuncu; Fulya Bayındır Bilman; Arzu Onur; Fikret Tekay. Evaluation of the Results Obtained from Microbiological Analysis of Blood Cultures over 5 Years. J. Fam. Med. Health Care 2016, 2(4), 43-50. doi: 10.11648/j.jfmhc.20160204.14

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AMA Style

Mine Turhanoglu, Esra Koyuncu, Fulya Bayındır Bilman, Arzu Onur, Fikret Tekay. Evaluation of the Results Obtained from Microbiological Analysis of Blood Cultures over 5 Years. J Fam Med Health Care. 2016;2(4):43-50. doi: 10.11648/j.jfmhc.20160204.14

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@article{10.11648/j.jfmhc.20160204.14,
  author = {Mine Turhanoglu and Esra Koyuncu and Fulya Bayındır Bilman and Arzu Onur and Fikret Tekay},
  title = {Evaluation of the Results Obtained from Microbiological Analysis of Blood Cultures over 5 Years},
  journal = {Journal of Family Medicine and Health Care},
  volume = {2},
  number = {4},
  pages = {43-50},
  doi = {10.11648/j.jfmhc.20160204.14},
  url = {https://doi.org/10.11648/j.jfmhc.20160204.14},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.jfmhc.20160204.14},
  abstract = {The infections caused by bacteria that reproduce in blood cultures are important medical problems that cause morbidity and mortality. The infections caused by resistant microorganisms are gradually increasing because of the patient’s long stay in hospital, invasive procedures, and application of multi and parenteral antibiotic treatment. The microorganisms that reproduced in the blood cultures of patients in different cultures between 2010-2015 in Diyarbakır Selahaddin Eyyübi State Hospital and the resistance of these microorganisms to antibiotics were assessed retrospectively. In the study, a total of 196 patients’ blood culture results were examined retrospectively. A total of 66.8% of the growth microorganisms (127) were composed of Gram positive cocci, 26.5% of them (52) were composed of Gram-negative bacilli and 6.7% of them (11) were composed of Candida spp. Among the reproduced microorganisms, coagulase negative staphylococci (CNS) were found to be 52.5% (103), Staphylococcus aureus to be 4.9% (9), Acinetobacter spp to be 7.3% (14), Escherichia coli to be 4.7% (9), Klebsiella spp to be 8.4% (16), Candida spp. to be 6.7% (11), Pseudomonas spp. to be 4.7% (9), Enterococcus faecalis to be 2% (4), Micrococcus luteus to be 2% (4), Kocuria kristinae to be 2.5% (5), Rhizobium radiobacter to be 0.5% (1), Leuconostoc mesenteroides subsp. cremoris to be 1% (1), Sphingomonas paucimobilis 0.5% (1), Pantoea spp. to be 0.5% (1), and Stenotrophomonas maltophilia to be 0.5% (1). The highest rate of resistance was found to be against meropenem, imipenem and ceftazidime in Acinetobacter spp with 80%, against ceftazidime in Klebsiella spp with 73.4%, against imipenem with 75%, against meropenem and ciprofloxacin with 62.5% in Pseudomonas aeruginosa, and against ceftriaxon, cefuroxime and cefuroxime axetil in Escherichia coli with 60%. Penicillin with 100% and tetracycline with 33.3% in S. aureus; penicillin with 97.6% and erythromycin with 82.1% were the antibiotics to which the highest resistance developed. While no resistance was determined against fusidic acid, trimethoprim sulfamethoxazole, linezolid, vancomycin, teicoplanin, and tigecycline in S. aureus, the resistance was not determined only against tigecycline and vancomycin in CNS. Fifty seven % of S. aureus strains and 83.8% of CNS strains were found to be resistant to methicillin. In our study, it is aimed to determine the mostly reproduced bacteria in blood samples as the result of blood circulation infections of patients staying in different clinics and to research their resistance profiles that developed against antibiotics retrospectively.},
 year = {2016}
}

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