The reaction of Ethyl 5-(piperidin-1-yl-methyl)furan-2-carboxylate with 4-amino salicylic acid afford a 4-(5-((diphenylamino)methyl)furan-2-carboxamido)-2-hydroxybenzoic acid (PFSA). The transition metal complexes of Cu2+, Co2+, Ni2+, Mn2+ and Zn2+ of PFSA have been prepared. The objective of the research work is synthesis, characterization and chelating properties of furan ring containing organic ligands. To monitor its antimicrobial activity. PFSA and all the metal complexes were characterized by elemental analyses, spectral studies, magnetic moment determination, molar conductivity measurement. The free ligand and it’s complexes have been tested for their antibacterial activities against two types of human pathogenic bacteria the first group is gram positive while the second group is gram negative (by using agar well diffusion method). Finally, it was found that compounds show different activity of inhibition on growth of the bacteria. The conclusion is Ni (II) Cu (II), Co (II) and Mn (II) complexes possess octahedral geometry around the central metal ion.
| Published in | Chemical and Biomolecular Engineering (Volume 5, Issue 1) |
| DOI | 10.11648/j.cbe.20200501.14 |
| Page(s) | 21-25 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
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Copyright © The Author(s), 2024. Published by Science Publishing Group |
Ethyl 5-(Piperidin-1-yl-methyl) Furan-2-Carboxylate, 4-Amino Salicylic Acid, Metal Chelates, Complexes, Spectral Studies, Magnetic Moment, Antibacterial and Antifungal Activity
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APA Style
Harshadkumar P. Patel. (2020). Analytical and Spectral Study of Furan Ring Containing Organic Ligands. Chemical and Biomolecular Engineering, 5(1), 21-25. https://doi.org/10.11648/j.cbe.20200501.14
ACS Style
Harshadkumar P. Patel. Analytical and Spectral Study of Furan Ring Containing Organic Ligands. Chem. Biomol. Eng. 2020, 5(1), 21-25. doi: 10.11648/j.cbe.20200501.14
AMA Style
Harshadkumar P. Patel. Analytical and Spectral Study of Furan Ring Containing Organic Ligands. Chem Biomol Eng. 2020;5(1):21-25. doi: 10.11648/j.cbe.20200501.14
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Download@article{10.11648/j.cbe.20200501.14,
author = {Harshadkumar P. Patel},
title = {Analytical and Spectral Study of Furan Ring Containing Organic Ligands},
journal = {Chemical and Biomolecular Engineering},
volume = {5},
number = {1},
pages = {21-25},
doi = {10.11648/j.cbe.20200501.14},
url = {https://doi.org/10.11648/j.cbe.20200501.14},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.cbe.20200501.14},
abstract = {The reaction of Ethyl 5-(piperidin-1-yl-methyl)furan-2-carboxylate with 4-amino salicylic acid afford a 4-(5-((diphenylamino)methyl)furan-2-carboxamido)-2-hydroxybenzoic acid (PFSA). The transition metal complexes of Cu2+, Co2+, Ni2+, Mn2+ and Zn2+ of PFSA have been prepared. The objective of the research work is synthesis, characterization and chelating properties of furan ring containing organic ligands. To monitor its antimicrobial activity. PFSA and all the metal complexes were characterized by elemental analyses, spectral studies, magnetic moment determination, molar conductivity measurement. The free ligand and it’s complexes have been tested for their antibacterial activities against two types of human pathogenic bacteria the first group is gram positive while the second group is gram negative (by using agar well diffusion method). Finally, it was found that compounds show different activity of inhibition on growth of the bacteria. The conclusion is Ni (II) Cu (II), Co (II) and Mn (II) complexes possess octahedral geometry around the central metal ion.},
year = {2020}
}
TY - JOUR T1 - Analytical and Spectral Study of Furan Ring Containing Organic Ligands AU - Harshadkumar P. Patel Y1 - 2020/01/30 PY - 2020 N1 - https://doi.org/10.11648/j.cbe.20200501.14 DO - 10.11648/j.cbe.20200501.14 T2 - Chemical and Biomolecular Engineering JF - Chemical and Biomolecular Engineering JO - Chemical and Biomolecular Engineering SP - 21 EP - 25 PB - Science Publishing Group SN - 2578-8884 UR - https://doi.org/10.11648/j.cbe.20200501.14 AB - The reaction of Ethyl 5-(piperidin-1-yl-methyl)furan-2-carboxylate with 4-amino salicylic acid afford a 4-(5-((diphenylamino)methyl)furan-2-carboxamido)-2-hydroxybenzoic acid (PFSA). The transition metal complexes of Cu2+, Co2+, Ni2+, Mn2+ and Zn2+ of PFSA have been prepared. The objective of the research work is synthesis, characterization and chelating properties of furan ring containing organic ligands. To monitor its antimicrobial activity. PFSA and all the metal complexes were characterized by elemental analyses, spectral studies, magnetic moment determination, molar conductivity measurement. The free ligand and it’s complexes have been tested for their antibacterial activities against two types of human pathogenic bacteria the first group is gram positive while the second group is gram negative (by using agar well diffusion method). Finally, it was found that compounds show different activity of inhibition on growth of the bacteria. The conclusion is Ni (II) Cu (II), Co (II) and Mn (II) complexes possess octahedral geometry around the central metal ion. VL - 5 IS - 1 ER -
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