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Microscopic Studies, Phytochemical and Biological Screenings of Ocimum canum

Received: 15 August 2019    Accepted: 7 October 2019    Published: 25 October 2019
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Abstract

It has been reported that more than 80% of the African population uses traditional medicine to primary healthcare. The aim of the study was to determine the histological elements, the phytochemical composition and evaluate the bioactivities of Ocimum canum in order to promote this plant used in Congolese traditional medicine. The earthworms were collected from the ponds of the secondary forest of Monastère Prieure Notre Dame de l’Assomption in Kinshasa city and the blood used in this study was provided by the Centre de Médecine Mixte et d’Anémie SS in Yolo-Sud quarter, Kinshasa, Democratic Republic of the Congo. The histological elements were determined by microscopic examination while different metabolites were determined using thin layer chromatography. Microscopic examination revealed the presence of crystalliferous fibres, fragment of parenchyma, grandular and non-glandular pluricellular trichomes, spheroidal pollen grains, diacytic stomata, spiral vessels. With regard to chromatographic analysis, phytochemicals identified were anthocyanins, coumarins, flavonoids, terpenoids and iridoids. The extracts from O. canum showed good antihelminthic, antisickling and antioxidant activities related to their phytochemicalsAll these findings constitute a scientific evidence validating the use of this medicinal plant for the management of various ailments in the Democratic Republic of the Congo.

Published in International Journal of Pharmacy and Chemistry (Volume 5, Issue 5)
DOI 10.11648/j.ijpc.20190505.13
Page(s) 61-67
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Antihelminthic Activity, Microscopic Features, Oleanolic Acid, Ocimum canum, Rosmarinic Acid

References
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    Dorothée Dinangayi Tshilanda, Clément Liyongo Inkoto, Kashala Mpongu, Souzane Mata, Paulin Kapepula Mutwale, et al. (2019). Microscopic Studies, Phytochemical and Biological Screenings of Ocimum canum. International Journal of Pharmacy and Chemistry, 5(5), 61-67. https://doi.org/10.11648/j.ijpc.20190505.13

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    Dorothée Dinangayi Tshilanda; Clément Liyongo Inkoto; Kashala Mpongu; Souzane Mata; Paulin Kapepula Mutwale, et al. Microscopic Studies, Phytochemical and Biological Screenings of Ocimum canum. Int. J. Pharm. Chem. 2019, 5(5), 61-67. doi: 10.11648/j.ijpc.20190505.13

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    AMA Style

    Dorothée Dinangayi Tshilanda, Clément Liyongo Inkoto, Kashala Mpongu, Souzane Mata, Paulin Kapepula Mutwale, et al. Microscopic Studies, Phytochemical and Biological Screenings of Ocimum canum. Int J Pharm Chem. 2019;5(5):61-67. doi: 10.11648/j.ijpc.20190505.13

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  • @article{10.11648/j.ijpc.20190505.13,
      author = {Dorothée Dinangayi Tshilanda and Clément Liyongo Inkoto and Kashala Mpongu and Souzane Mata and Paulin Kapepula Mutwale and Damien Sha-Tshibey Tshibangu and Gédéon Ngiala Bongo and Ngbolua Koto-te-Nyiwa and Pius Tshimankinda Mpiana},
      title = {Microscopic Studies, Phytochemical and Biological Screenings of Ocimum canum},
      journal = {International Journal of Pharmacy and Chemistry},
      volume = {5},
      number = {5},
      pages = {61-67},
      doi = {10.11648/j.ijpc.20190505.13},
      url = {https://doi.org/10.11648/j.ijpc.20190505.13},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijpc.20190505.13},
      abstract = {It has been reported that more than 80% of the African population uses traditional medicine to primary healthcare. The aim of the study was to determine the histological elements, the phytochemical composition and evaluate the bioactivities of Ocimum canum in order to promote this plant used in Congolese traditional medicine. The earthworms were collected from the ponds of the secondary forest of Monastère Prieure Notre Dame de l’Assomption in Kinshasa city and the blood used in this study was provided by the Centre de Médecine Mixte et d’Anémie SS in Yolo-Sud quarter, Kinshasa, Democratic Republic of the Congo. The histological elements were determined by microscopic examination while different metabolites were determined using thin layer chromatography. Microscopic examination revealed the presence of crystalliferous fibres, fragment of parenchyma, grandular and non-glandular pluricellular trichomes, spheroidal pollen grains, diacytic stomata, spiral vessels. With regard to chromatographic analysis, phytochemicals identified were anthocyanins, coumarins, flavonoids, terpenoids and iridoids. The extracts from O. canum showed good antihelminthic, antisickling and antioxidant activities related to their phytochemicalsAll these findings constitute a scientific evidence validating the use of this medicinal plant for the management of various ailments in the Democratic Republic of the Congo.},
     year = {2019}
    }
    

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  • TY  - JOUR
    T1  - Microscopic Studies, Phytochemical and Biological Screenings of Ocimum canum
    AU  - Dorothée Dinangayi Tshilanda
    AU  - Clément Liyongo Inkoto
    AU  - Kashala Mpongu
    AU  - Souzane Mata
    AU  - Paulin Kapepula Mutwale
    AU  - Damien Sha-Tshibey Tshibangu
    AU  - Gédéon Ngiala Bongo
    AU  - Ngbolua Koto-te-Nyiwa
    AU  - Pius Tshimankinda Mpiana
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    DO  - 10.11648/j.ijpc.20190505.13
    T2  - International Journal of Pharmacy and Chemistry
    JF  - International Journal of Pharmacy and Chemistry
    JO  - International Journal of Pharmacy and Chemistry
    SP  - 61
    EP  - 67
    PB  - Science Publishing Group
    SN  - 2575-5749
    UR  - https://doi.org/10.11648/j.ijpc.20190505.13
    AB  - It has been reported that more than 80% of the African population uses traditional medicine to primary healthcare. The aim of the study was to determine the histological elements, the phytochemical composition and evaluate the bioactivities of Ocimum canum in order to promote this plant used in Congolese traditional medicine. The earthworms were collected from the ponds of the secondary forest of Monastère Prieure Notre Dame de l’Assomption in Kinshasa city and the blood used in this study was provided by the Centre de Médecine Mixte et d’Anémie SS in Yolo-Sud quarter, Kinshasa, Democratic Republic of the Congo. The histological elements were determined by microscopic examination while different metabolites were determined using thin layer chromatography. Microscopic examination revealed the presence of crystalliferous fibres, fragment of parenchyma, grandular and non-glandular pluricellular trichomes, spheroidal pollen grains, diacytic stomata, spiral vessels. With regard to chromatographic analysis, phytochemicals identified were anthocyanins, coumarins, flavonoids, terpenoids and iridoids. The extracts from O. canum showed good antihelminthic, antisickling and antioxidant activities related to their phytochemicalsAll these findings constitute a scientific evidence validating the use of this medicinal plant for the management of various ailments in the Democratic Republic of the Congo.
    VL  - 5
    IS  - 5
    ER  - 

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Author Information
  • Department of Chemistry, Faculty of Sciences, University of Kinshasa, Kinshasa, Democratic Republic of the Congo

  • Department of Nutrition, Public Health School, Faculty of Medicine, University of Kinshasa, Kinshasa, Democratic Republic of the Congo

  • Department of Chemistry, Faculty of Sciences, University of Kinshasa, Kinshasa, Democratic Republic of the Congo

  • Department of Biology, Faculty of Sciences, University of Kinshasa, Kinshasa, Democratic Republic of the Congo

  • Centre d’Etudes des Substances Naturelles d’Origine Végétale (CESNOV), Faculty of Pharmaceutical Sciences, University of Kinshasa, Kinshasa, Democratic Republic of the Congo

  • Department of Chemistry, Faculty of Sciences, University of Kinshasa, Kinshasa, Democratic Republic of the Congo

  • Department of Biology, Faculty of Sciences, University of Kinshasa, Kinshasa, Democratic Republic of the Congo

  • Department of Biology, Faculty of Sciences, University of Kinshasa, Kinshasa, Democratic Republic of the Congo

  • Department of Chemistry, Faculty of Sciences, University of Kinshasa, Kinshasa, Democratic Republic of the Congo

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