Objective: Placental mesenchymal dysplasia (PDM) is a rare disease, the cause is unknown, some are called mesenchymal stem hyperplasia, and some are called pseudo-vesicular block or vascular malformation. The aim is to report the clinical and pathologic characteristics of three cases of placental mesenchymal dysplasia (PMD). Method: Pathologic and clinical data were retrieved from the electronic medical records. The data were reviewed and summarized by the same pathologist. Results: Maternal age was respective 36 years, 31 years and 33 years. Cesarean section was performed at 39 weeks, 37 weeks and 38 weeks, respectively. The newborns were born with birth weight of 1790, 2370 and 3150 grams, respectively, with placenta weight of 590, 579 and 510 grams respectively. Placenta for pathological examination was performed macroscopically thick-walled vessels. Microscopic observation showed that the part of the stem villus was saclikely dilated, the blood vessels were thickened in the villi, the blood vessel wall was thickened, the villus interstitial was loose, and the mucus was changed. Part of the villus edema and degeneration, no trophoblastic hyperplasia, the final villus structure is normal. Conclusion: The size of the lesions in the Placental mesenchymal dysplasia and the location of the lesion is closely related to the birth weight of the newborn. Detailed histology is necessary for diagnosis and differential diagnosis.
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International Journal of Clinical and Experimental Medical Sciences (Volume 6, Issue 1)
This article belongs to the Special Issue Pathology |
| DOI | 10.11648/j.ijcems.20200601.11 |
| Page(s) | 1-4 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2024. Published by Science Publishing Group |
Placental Developmental Abnormality, Placental Disease, Vascular Disease, Hydatidiform Mole
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| [8] | Takahashi H, Matsubara S, Kuwata T, et al. Changes in expression of vascular endothelial growth factor D-related genes in placental mesenchymal dysplasia [J]. J Obstet Gynaecol Res. 2014, 40 (4): 1145-9. |
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APA Style
Yanqing Kong, Yanrui Zhang, Hongping Tang, Xueyu Chen. (2020). Case Series of Placental Mesenchymal Dysplasia with Live Birth. International Journal of Clinical and Experimental Medical Sciences, 6(1), 1-4. https://doi.org/10.11648/j.ijcems.20200601.11
ACS Style
Yanqing Kong; Yanrui Zhang; Hongping Tang; Xueyu Chen. Case Series of Placental Mesenchymal Dysplasia with Live Birth. Int. J. Clin. Exp. Med. Sci. 2020, 6(1), 1-4. doi: 10.11648/j.ijcems.20200601.11
AMA Style
Yanqing Kong, Yanrui Zhang, Hongping Tang, Xueyu Chen. Case Series of Placental Mesenchymal Dysplasia with Live Birth. Int J Clin Exp Med Sci. 2020;6(1):1-4. doi: 10.11648/j.ijcems.20200601.11
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Download@article{10.11648/j.ijcems.20200601.11,
author = {Yanqing Kong and Yanrui Zhang and Hongping Tang and Xueyu Chen},
title = {Case Series of Placental Mesenchymal Dysplasia with Live Birth},
journal = {International Journal of Clinical and Experimental Medical Sciences},
volume = {6},
number = {1},
pages = {1-4},
doi = {10.11648/j.ijcems.20200601.11},
url = {https://doi.org/10.11648/j.ijcems.20200601.11},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijcems.20200601.11},
abstract = {Objective: Placental mesenchymal dysplasia (PDM) is a rare disease, the cause is unknown, some are called mesenchymal stem hyperplasia, and some are called pseudo-vesicular block or vascular malformation. The aim is to report the clinical and pathologic characteristics of three cases of placental mesenchymal dysplasia (PMD). Method: Pathologic and clinical data were retrieved from the electronic medical records. The data were reviewed and summarized by the same pathologist. Results: Maternal age was respective 36 years, 31 years and 33 years. Cesarean section was performed at 39 weeks, 37 weeks and 38 weeks, respectively. The newborns were born with birth weight of 1790, 2370 and 3150 grams, respectively, with placenta weight of 590, 579 and 510 grams respectively. Placenta for pathological examination was performed macroscopically thick-walled vessels. Microscopic observation showed that the part of the stem villus was saclikely dilated, the blood vessels were thickened in the villi, the blood vessel wall was thickened, the villus interstitial was loose, and the mucus was changed. Part of the villus edema and degeneration, no trophoblastic hyperplasia, the final villus structure is normal. Conclusion: The size of the lesions in the Placental mesenchymal dysplasia and the location of the lesion is closely related to the birth weight of the newborn. Detailed histology is necessary for diagnosis and differential diagnosis.},
year = {2020}
}
TY - JOUR T1 - Case Series of Placental Mesenchymal Dysplasia with Live Birth AU - Yanqing Kong AU - Yanrui Zhang AU - Hongping Tang AU - Xueyu Chen Y1 - 2020/01/02 PY - 2020 N1 - https://doi.org/10.11648/j.ijcems.20200601.11 DO - 10.11648/j.ijcems.20200601.11 T2 - International Journal of Clinical and Experimental Medical Sciences JF - International Journal of Clinical and Experimental Medical Sciences JO - International Journal of Clinical and Experimental Medical Sciences SP - 1 EP - 4 PB - Science Publishing Group SN - 2469-8032 UR - https://doi.org/10.11648/j.ijcems.20200601.11 AB - Objective: Placental mesenchymal dysplasia (PDM) is a rare disease, the cause is unknown, some are called mesenchymal stem hyperplasia, and some are called pseudo-vesicular block or vascular malformation. The aim is to report the clinical and pathologic characteristics of three cases of placental mesenchymal dysplasia (PMD). Method: Pathologic and clinical data were retrieved from the electronic medical records. The data were reviewed and summarized by the same pathologist. Results: Maternal age was respective 36 years, 31 years and 33 years. Cesarean section was performed at 39 weeks, 37 weeks and 38 weeks, respectively. The newborns were born with birth weight of 1790, 2370 and 3150 grams, respectively, with placenta weight of 590, 579 and 510 grams respectively. Placenta for pathological examination was performed macroscopically thick-walled vessels. Microscopic observation showed that the part of the stem villus was saclikely dilated, the blood vessels were thickened in the villi, the blood vessel wall was thickened, the villus interstitial was loose, and the mucus was changed. Part of the villus edema and degeneration, no trophoblastic hyperplasia, the final villus structure is normal. Conclusion: The size of the lesions in the Placental mesenchymal dysplasia and the location of the lesion is closely related to the birth weight of the newborn. Detailed histology is necessary for diagnosis and differential diagnosis. VL - 6 IS - 1 ER -
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