American Journal of Heterocyclic Chemistry

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Antimicrobial Activity of Mn Complexes Incorporating Schiff Bases: A Short Review

Received: May 08, 2019    Accepted: Jun. 12, 2019    Published: Jul. 01, 2019
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Abstract

Antibiotic resistance has been growing at an anxious rate and as a result the activity of antibiotics against Gram-negative and Gram-positive bacteria has dropped dramatically day by day. Metal ions play many critical functions in humans. Deficiency of some metal ions can lead to disease like pernicious anemia, growth retardation, heart disease in infants etc. In this sense there is a strong need to synthesis new substances that not only have good spectrum of activity, but having new mechanisms of action. Inorganic compounds particularly Mn metal complexes have played an important role in the development of new metal based drugs. Over the past few years, there have been many reports on their applications in homogeneous and heterogeneous catalysis. The activity is usually increased by complexation therefore to understand the properties of both ligands and metal can lead to the synthesis of highly active compounds. The influence of certain metals on the biological activity of these compounds and their intrinsic chemical interest as multidentate ligands has prompted a considerable increase in the study of their coordination behavior. Development of a new chemotherapeutic Schiff bases and their metal complexes is now attracting the attention of medicinal chemists. In this review we have focused on research of Mn complexes incorporation of Schiff bases carry out over the past few decades which has sought to possess preclinical pharmacological screenings like anti-bacterial, anti-fungal, anti-tuberculosis, anti-inflammatory, anti-cancer, DNA- interaction and anti-tumor action of synthetic metal complexes.

DOI 10.11648/j.ajhc.20190502.12
Published in American Journal of Heterocyclic Chemistry ( Volume 5, Issue 2, June 2019 )
Page(s) 27-36
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Schiff Bases, Mn Complexes, Metal Based Drugs, Antibacterial, Anti-Inflammatory

References
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Cite This Article
  • APA Style

    Sharif Uddin, Md. Saddam Hossain, Md. Abdul Latif, Md. Rabiul karim, Ranjan K. Mohapatra, et al. (2019). Antimicrobial Activity of Mn Complexes Incorporating Schiff Bases: A Short Review. American Journal of Heterocyclic Chemistry, 5(2), 27-36. https://doi.org/10.11648/j.ajhc.20190502.12

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    ACS Style

    Sharif Uddin; Md. Saddam Hossain; Md. Abdul Latif; Md. Rabiul karim; Ranjan K. Mohapatra, et al. Antimicrobial Activity of Mn Complexes Incorporating Schiff Bases: A Short Review. Am. J. Heterocycl. Chem. 2019, 5(2), 27-36. doi: 10.11648/j.ajhc.20190502.12

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    AMA Style

    Sharif Uddin, Md. Saddam Hossain, Md. Abdul Latif, Md. Rabiul karim, Ranjan K. Mohapatra, et al. Antimicrobial Activity of Mn Complexes Incorporating Schiff Bases: A Short Review. Am J Heterocycl Chem. 2019;5(2):27-36. doi: 10.11648/j.ajhc.20190502.12

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  • @article{10.11648/j.ajhc.20190502.12,
      author = {Sharif Uddin and Md. Saddam Hossain and Md. Abdul Latif and Md. Rabiul karim and Ranjan K. Mohapatra and Md. Kudrat-E-Zahan},
      title = {Antimicrobial Activity of Mn Complexes Incorporating Schiff Bases: A Short Review},
      journal = {American Journal of Heterocyclic Chemistry},
      volume = {5},
      number = {2},
      pages = {27-36},
      doi = {10.11648/j.ajhc.20190502.12},
      url = {https://doi.org/10.11648/j.ajhc.20190502.12},
      eprint = {https://download.sciencepg.com/pdf/10.11648.j.ajhc.20190502.12},
      abstract = {Antibiotic resistance has been growing at an anxious rate and as a result the activity of antibiotics against Gram-negative and Gram-positive bacteria has dropped dramatically day by day. Metal ions play many critical functions in humans. Deficiency of some metal ions can lead to disease like pernicious anemia, growth retardation, heart disease in infants etc. In this sense there is a strong need to synthesis new substances that not only have good spectrum of activity, but having new mechanisms of action. Inorganic compounds particularly Mn metal complexes have played an important role in the development of new metal based drugs. Over the past few years, there have been many reports on their applications in homogeneous and heterogeneous catalysis. The activity is usually increased by complexation therefore to understand the properties of both ligands and metal can lead to the synthesis of highly active compounds. The influence of certain metals on the biological activity of these compounds and their intrinsic chemical interest as multidentate ligands has prompted a considerable increase in the study of their coordination behavior. Development of a new chemotherapeutic Schiff bases and their metal complexes is now attracting the attention of medicinal chemists. In this review we have focused on research of Mn complexes incorporation of Schiff bases carry out over the past few decades which has sought to possess preclinical pharmacological screenings like anti-bacterial, anti-fungal, anti-tuberculosis, anti-inflammatory, anti-cancer, DNA- interaction and anti-tumor action of synthetic metal complexes.},
     year = {2019}
    }
    

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  • TY  - JOUR
    T1  - Antimicrobial Activity of Mn Complexes Incorporating Schiff Bases: A Short Review
    AU  - Sharif Uddin
    AU  - Md. Saddam Hossain
    AU  - Md. Abdul Latif
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    T2  - American Journal of Heterocyclic Chemistry
    JF  - American Journal of Heterocyclic Chemistry
    JO  - American Journal of Heterocyclic Chemistry
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    EP  - 36
    PB  - Science Publishing Group
    SN  - 2575-5722
    UR  - https://doi.org/10.11648/j.ajhc.20190502.12
    AB  - Antibiotic resistance has been growing at an anxious rate and as a result the activity of antibiotics against Gram-negative and Gram-positive bacteria has dropped dramatically day by day. Metal ions play many critical functions in humans. Deficiency of some metal ions can lead to disease like pernicious anemia, growth retardation, heart disease in infants etc. In this sense there is a strong need to synthesis new substances that not only have good spectrum of activity, but having new mechanisms of action. Inorganic compounds particularly Mn metal complexes have played an important role in the development of new metal based drugs. Over the past few years, there have been many reports on their applications in homogeneous and heterogeneous catalysis. The activity is usually increased by complexation therefore to understand the properties of both ligands and metal can lead to the synthesis of highly active compounds. The influence of certain metals on the biological activity of these compounds and their intrinsic chemical interest as multidentate ligands has prompted a considerable increase in the study of their coordination behavior. Development of a new chemotherapeutic Schiff bases and their metal complexes is now attracting the attention of medicinal chemists. In this review we have focused on research of Mn complexes incorporation of Schiff bases carry out over the past few decades which has sought to possess preclinical pharmacological screenings like anti-bacterial, anti-fungal, anti-tuberculosis, anti-inflammatory, anti-cancer, DNA- interaction and anti-tumor action of synthetic metal complexes.
    VL  - 5
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Author Information
  • Department of Chemistry, Rajshahi University, Rajshahi, Bangladesh

  • Department of Chemistry, Begum Rokeya University, Rangpur, Bangladesh

  • Department of Chemistry, Begum Rokeya University, Rangpur, Bangladesh

  • Department of Chemistry, Rajshahi University, Rajshahi, Bangladesh

  • Department of Chemistry, Government College of Engineering, Keonjhar, Odisha, India

  • Department of Chemistry, Rajshahi University, Rajshahi, Bangladesh

  • Section