Seroprevalence of Herpes Simplex Virus Type 2 and HIV Co-Infection Among Pregnant Women in Jigawa State

Amoo Florence Kemi; Sani Nura Muhammad; Gumel Ahmad Muhammad; Eze Lovelyn Chinyere; Nafisat Baita; Mukhtar Sa’adatu Ismail; Dauda Hauwa Sani

doi:doi:10.11648/j.ijmb.20200501.11

Seroprevalence of Herpes Simplex Virus Type 2 and HIV Co-Infection Among Pregnant Women in Jigawa State

Amoo Florence Kemi, Sani Nura Muhammad, Gumel Ahmad Muhammad, Eze Lovelyn Chinyere, Nafisat Baita, Mukhtar Sa’adatu Ismail, Dauda Hauwa Sani

Published in International Journal of Microbiology and Biotechnology (Volume 5, Issue 1)

Received: 11 December 2019 Accepted: 25 December 2019 Published: 8 January 2020

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Abstract

Herpes simplex virus type 2 (HSV-2) infections is one of the most common sexually transmitted infections Worldwide. It facilitates the acquisition of HIV and is the primary cause of genital herpes which when acquired by women during pregnancy account for half of the mobidity and mortality among neonates. Lifelong latent HSV-2 infection raises concern among women of reproductive age considering the risk of neonatal transmission. In Nigeria screening for HSV-2 and co-infection with HIV in antenatal clinics is not routinely done. A cross-sectional study, was carried out among pregnant women attending antenatal clinics in four hospitals in Jigawa state. A total of 300 consenting pregnant women were enrolled, the study involved collection of sociodemographic data and laboratory determination of HSV-2 immunoglobulin G (IgG) and HIV seroprevalence using WHO standard procedure of Enzyme Linked Immunosorbent Assay (ELISA) test kit (DIAPRO Diagnostic Bioprobes, Milano, Italy), UNI-GOLD Wicklow, Ireland and ALERE Determine, respectively. Statistical significance was determined at p<0.05Of the 300 samples tested, overall seroprevalence of 55 (18.3%) and 44 (14.7%) for HSV-2 and HIV were recorded. The HSV-2 and HIV Co-infection rate was 16 (5.3%) among respondent. About 87.5% of the co-infection occurred in respondents that were in their 2^nd Trimester. Addionally, co-infection was found to be high among respondents between the age of 15-34yrs with 81.3%. In this study, education status, parity, stage of pregnancy, occupation, History of blood transfusion had no statistical significance with HSV-2 and HIV co-infection (p>0.05). This study has demonstrated the existence and risk of neonatal herpes in the study area. It is recommended that HSV testing should be placed among the standard medical checkup tests in the area, again advocacy and public awareness on the potential public health burden of HSV-2 and HIV co-infection should be observed.

Published in	International Journal of Microbiology and Biotechnology (Volume 5, Issue 1)
DOI	10.11648/j.ijmb.20200501.11
Page(s)	1-6
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

HIV, HSV-2, Virus, Co-infection, ELISA, STIs, Neonatal

References

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APA Style

Amoo Florence Kemi, Sani Nura Muhammad, Gumel Ahmad Muhammad, Eze Lovelyn Chinyere, Nafisat Baita, et al. (2020). Seroprevalence of Herpes Simplex Virus Type 2 and HIV Co-Infection Among Pregnant Women in Jigawa State. International Journal of Microbiology and Biotechnology, 5(1), 1-6. https://doi.org/10.11648/j.ijmb.20200501.11

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ACS Style

Amoo Florence Kemi; Sani Nura Muhammad; Gumel Ahmad Muhammad; Eze Lovelyn Chinyere; Nafisat Baita, et al. Seroprevalence of Herpes Simplex Virus Type 2 and HIV Co-Infection Among Pregnant Women in Jigawa State. Int. J. Microbiol. Biotechnol. 2020, 5(1), 1-6. doi: 10.11648/j.ijmb.20200501.11

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AMA Style

Amoo Florence Kemi, Sani Nura Muhammad, Gumel Ahmad Muhammad, Eze Lovelyn Chinyere, Nafisat Baita, et al. Seroprevalence of Herpes Simplex Virus Type 2 and HIV Co-Infection Among Pregnant Women in Jigawa State. Int J Microbiol Biotechnol. 2020;5(1):1-6. doi: 10.11648/j.ijmb.20200501.11

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@article{10.11648/j.ijmb.20200501.11,
  author = {Amoo Florence Kemi and Sani Nura Muhammad and Gumel Ahmad Muhammad and Eze Lovelyn Chinyere and Nafisat Baita and Mukhtar Sa’adatu Ismail and Dauda Hauwa Sani},
  title = {Seroprevalence of Herpes Simplex Virus Type 2 and HIV Co-Infection Among Pregnant Women in Jigawa State},
  journal = {International Journal of Microbiology and Biotechnology},
  volume = {5},
  number = {1},
  pages = {1-6},
  doi = {10.11648/j.ijmb.20200501.11},
  url = {https://doi.org/10.11648/j.ijmb.20200501.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijmb.20200501.11},
  abstract = {Herpes simplex virus type 2 (HSV-2) infections is one of the most common sexually transmitted infections Worldwide. It facilitates the acquisition of HIV and is the primary cause of genital herpes which when acquired by women during pregnancy account for half of the mobidity and mortality among neonates. Lifelong latent HSV-2 infection raises concern among women of reproductive age considering the risk of neonatal transmission. In Nigeria screening for HSV-2 and co-infection with HIV in antenatal clinics is not routinely done. A cross-sectional study, was carried out among pregnant women attending antenatal clinics in four hospitals in Jigawa state. A total of 300 consenting pregnant women were enrolled, the study involved collection of sociodemographic data and laboratory determination of HSV-2 immunoglobulin G (IgG) and HIV seroprevalence using WHO standard procedure of Enzyme Linked Immunosorbent Assay (ELISA) test kit (DIAPRO Diagnostic Bioprobes, Milano, Italy), UNI-GOLD Wicklow, Ireland and ALERE Determine, respectively. Statistical significance was determined at pnd Trimester. Addionally, co-infection was found to be high among respondents between the age of 15-34yrs with 81.3%. In this study, education status, parity, stage of pregnancy, occupation, History of blood transfusion had no statistical significance with HSV-2 and HIV co-infection (p>0.05). This study has demonstrated the existence and risk of neonatal herpes in the study area. It is recommended that HSV testing should be placed among the standard medical checkup tests in the area, again advocacy and public awareness on the potential public health burden of HSV-2 and HIV co-infection should be observed.},
 year = {2020}
}

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TY  - JOUR
T1  - Seroprevalence of Herpes Simplex Virus Type 2 and HIV Co-Infection Among Pregnant Women in Jigawa State
AU  - Amoo Florence Kemi
AU  - Sani Nura Muhammad
AU  - Gumel Ahmad Muhammad
AU  - Eze Lovelyn Chinyere
AU  - Nafisat Baita
AU  - Mukhtar Sa’adatu Ismail
AU  - Dauda Hauwa Sani
Y1  - 2020/01/08
PY  - 2020
N1  - https://doi.org/10.11648/j.ijmb.20200501.11
DO  - 10.11648/j.ijmb.20200501.11
T2  - International Journal of Microbiology and Biotechnology
JF  - International Journal of Microbiology and Biotechnology
JO  - International Journal of Microbiology and Biotechnology
SP  - 1
EP  - 6
PB  - Science Publishing Group
SN  - 2578-9686
UR  - https://doi.org/10.11648/j.ijmb.20200501.11
AB  - Herpes simplex virus type 2 (HSV-2) infections is one of the most common sexually transmitted infections Worldwide. It facilitates the acquisition of HIV and is the primary cause of genital herpes which when acquired by women during pregnancy account for half of the mobidity and mortality among neonates. Lifelong latent HSV-2 infection raises concern among women of reproductive age considering the risk of neonatal transmission. In Nigeria screening for HSV-2 and co-infection with HIV in antenatal clinics is not routinely done. A cross-sectional study, was carried out among pregnant women attending antenatal clinics in four hospitals in Jigawa state. A total of 300 consenting pregnant women were enrolled, the study involved collection of sociodemographic data and laboratory determination of HSV-2 immunoglobulin G (IgG) and HIV seroprevalence using WHO standard procedure of Enzyme Linked Immunosorbent Assay (ELISA) test kit (DIAPRO Diagnostic Bioprobes, Milano, Italy), UNI-GOLD Wicklow, Ireland and ALERE Determine, respectively. Statistical significance was determined at pnd Trimester. Addionally, co-infection was found to be high among respondents between the age of 15-34yrs with 81.3%. In this study, education status, parity, stage of pregnancy, occupation, History of blood transfusion had no statistical significance with HSV-2 and HIV co-infection (p>0.05). This study has demonstrated the existence and risk of neonatal herpes in the study area. It is recommended that HSV testing should be placed among the standard medical checkup tests in the area, again advocacy and public awareness on the potential public health burden of HSV-2 and HIV co-infection should be observed.
VL  - 5
IS  - 1
ER  -

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Author Information

Amoo Florence Kemi

Department of Microbiology and Biotechnology, Faculty of Science, Federal University, Dutse, Nigeria
Sani Nura Muhammad

Department of Microbiology and Biotechnology, Faculty of Science, Federal University, Dutse, Nigeria
Gumel Ahmad Muhammad

Department of Microbiology and Biotechnology, Faculty of Science, Federal University, Dutse, Nigeria
Eze Lovelyn Chinyere

Department of Microbiology and Biotechnology, Faculty of Science, Federal University, Dutse, Nigeria
Nafisat Baita

Department of Microbiology and Biotechnology, Faculty of Science, Federal University, Dutse, Nigeria
Mukhtar Sa’adatu Ismail

Department of Microbiology and Biotechnology, Faculty of Science, Federal University, Dutse, Nigeria
Dauda Hauwa Sani

Department of Microbiology and Biotechnology, Faculty of Science, Federal University, Dutse, Nigeria

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APA Style

Amoo Florence Kemi, Sani Nura Muhammad, Gumel Ahmad Muhammad, Eze Lovelyn Chinyere, Nafisat Baita, et al. (2020). Seroprevalence of Herpes Simplex Virus Type 2 and HIV Co-Infection Among Pregnant Women in Jigawa State. International Journal of Microbiology and Biotechnology, 5(1), 1-6. https://doi.org/10.11648/j.ijmb.20200501.11

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ACS Style

Amoo Florence Kemi; Sani Nura Muhammad; Gumel Ahmad Muhammad; Eze Lovelyn Chinyere; Nafisat Baita, et al. Seroprevalence of Herpes Simplex Virus Type 2 and HIV Co-Infection Among Pregnant Women in Jigawa State. Int. J. Microbiol. Biotechnol. 2020, 5(1), 1-6. doi: 10.11648/j.ijmb.20200501.11

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AMA Style

Amoo Florence Kemi, Sani Nura Muhammad, Gumel Ahmad Muhammad, Eze Lovelyn Chinyere, Nafisat Baita, et al. Seroprevalence of Herpes Simplex Virus Type 2 and HIV Co-Infection Among Pregnant Women in Jigawa State. Int J Microbiol Biotechnol. 2020;5(1):1-6. doi: 10.11648/j.ijmb.20200501.11

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@article{10.11648/j.ijmb.20200501.11,
  author = {Amoo Florence Kemi and Sani Nura Muhammad and Gumel Ahmad Muhammad and Eze Lovelyn Chinyere and Nafisat Baita and Mukhtar Sa’adatu Ismail and Dauda Hauwa Sani},
  title = {Seroprevalence of Herpes Simplex Virus Type 2 and HIV Co-Infection Among Pregnant Women in Jigawa State},
  journal = {International Journal of Microbiology and Biotechnology},
  volume = {5},
  number = {1},
  pages = {1-6},
  doi = {10.11648/j.ijmb.20200501.11},
  url = {https://doi.org/10.11648/j.ijmb.20200501.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijmb.20200501.11},
  abstract = {Herpes simplex virus type 2 (HSV-2) infections is one of the most common sexually transmitted infections Worldwide. It facilitates the acquisition of HIV and is the primary cause of genital herpes which when acquired by women during pregnancy account for half of the mobidity and mortality among neonates. Lifelong latent HSV-2 infection raises concern among women of reproductive age considering the risk of neonatal transmission. In Nigeria screening for HSV-2 and co-infection with HIV in antenatal clinics is not routinely done. A cross-sectional study, was carried out among pregnant women attending antenatal clinics in four hospitals in Jigawa state. A total of 300 consenting pregnant women were enrolled, the study involved collection of sociodemographic data and laboratory determination of HSV-2 immunoglobulin G (IgG) and HIV seroprevalence using WHO standard procedure of Enzyme Linked Immunosorbent Assay (ELISA) test kit (DIAPRO Diagnostic Bioprobes, Milano, Italy), UNI-GOLD Wicklow, Ireland and ALERE Determine, respectively. Statistical significance was determined at pnd Trimester. Addionally, co-infection was found to be high among respondents between the age of 15-34yrs with 81.3%. In this study, education status, parity, stage of pregnancy, occupation, History of blood transfusion had no statistical significance with HSV-2 and HIV co-infection (p>0.05). This study has demonstrated the existence and risk of neonatal herpes in the study area. It is recommended that HSV testing should be placed among the standard medical checkup tests in the area, again advocacy and public awareness on the potential public health burden of HSV-2 and HIV co-infection should be observed.},
 year = {2020}
}

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TY  - JOUR
T1  - Seroprevalence of Herpes Simplex Virus Type 2 and HIV Co-Infection Among Pregnant Women in Jigawa State
AU  - Amoo Florence Kemi
AU  - Sani Nura Muhammad
AU  - Gumel Ahmad Muhammad
AU  - Eze Lovelyn Chinyere
AU  - Nafisat Baita
AU  - Mukhtar Sa’adatu Ismail
AU  - Dauda Hauwa Sani
Y1  - 2020/01/08
PY  - 2020
N1  - https://doi.org/10.11648/j.ijmb.20200501.11
DO  - 10.11648/j.ijmb.20200501.11
T2  - International Journal of Microbiology and Biotechnology
JF  - International Journal of Microbiology and Biotechnology
JO  - International Journal of Microbiology and Biotechnology
SP  - 1
EP  - 6
PB  - Science Publishing Group
SN  - 2578-9686
UR  - https://doi.org/10.11648/j.ijmb.20200501.11
AB  - Herpes simplex virus type 2 (HSV-2) infections is one of the most common sexually transmitted infections Worldwide. It facilitates the acquisition of HIV and is the primary cause of genital herpes which when acquired by women during pregnancy account for half of the mobidity and mortality among neonates. Lifelong latent HSV-2 infection raises concern among women of reproductive age considering the risk of neonatal transmission. In Nigeria screening for HSV-2 and co-infection with HIV in antenatal clinics is not routinely done. A cross-sectional study, was carried out among pregnant women attending antenatal clinics in four hospitals in Jigawa state. A total of 300 consenting pregnant women were enrolled, the study involved collection of sociodemographic data and laboratory determination of HSV-2 immunoglobulin G (IgG) and HIV seroprevalence using WHO standard procedure of Enzyme Linked Immunosorbent Assay (ELISA) test kit (DIAPRO Diagnostic Bioprobes, Milano, Italy), UNI-GOLD Wicklow, Ireland and ALERE Determine, respectively. Statistical significance was determined at pnd Trimester. Addionally, co-infection was found to be high among respondents between the age of 15-34yrs with 81.3%. In this study, education status, parity, stage of pregnancy, occupation, History of blood transfusion had no statistical significance with HSV-2 and HIV co-infection (p>0.05). This study has demonstrated the existence and risk of neonatal herpes in the study area. It is recommended that HSV testing should be placed among the standard medical checkup tests in the area, again advocacy and public awareness on the potential public health burden of HSV-2 and HIV co-infection should be observed.
VL  - 5
IS  - 1
ER  -

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