European Journal of Preventive Medicine

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Incidence and Risk Factors of Peripherally Inserted Central Catheter-related Complications in Patients with Different Disease Types

Received: Sep. 29, 2019    Accepted: Oct. 31, 2019    Published: Nov. 07, 2019
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Abstract

Background: Cancer patients or critical patients need reliable vascular access to meet the requirements of transporting therapeutic drugs or nutrients. Peripherally inserted central catheters (PICCs) are widely used in these patients, however, the incidence of PICC-related complications is high and the data on specific diseases are not yet clear. Methods: We collected geographic characteristics and insertion information of patients with lung cancer, breast cancer, digestive tract tumor and ICU status who underwent PICC during May 2017 to June 2018. Univariate and multivariate analysis were used to estimate the risk factors of PICC-related complications. Results: 634 lung cancer, 979 breast cancer, 1453 digestive tract cancer, and 374 ICU status patients were enrolled in the study with 351 (10.2%) developed complications. There was no difference in the distribution of complications among different disease types (P>0.05). Drinking (OR 2.15, 95 CI% 1.05-3.69, P=0.012) and prior surgery (OR 1.97, 95% CI 1.05-3.69, P=0.035) were risk factors of breast cancer patients. Prior surgery (OR 2.51, 95% CI 1.54-4.09, P<0.001) and site of PICC (OR 1.56, 95% CI 1.10-2.23, P=0.014) were the influenced factors of digestive tract tumor patients. Complications of ICU status patients were influenced by smoke (OR 5.83, 95% CI 1.30-26.14, P=0.021) and prior surgery (OR 3.43, 95% CI 1.44-8.13, P=0.005). Conclusion: The targeted and reasonable prevention and nursing care should be focused on by medical staff.

DOI 10.11648/j.ejpm.20190706.13
Published in European Journal of Preventive Medicine ( Volume 7, Issue 6, December 2019 )
Page(s) 108-111
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This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2024. Published by Science Publishing Group

Keywords

Peripherally Inserted Central Catheters, Disease Type, Complications, Risk Factors

References
[1] Cotogni P, Barbero C, Garrino C, et al. Peripherally inserted central catheters in non-hospitalized cancer patients: 5-year results of a prospective study. Supportive care in cancer: official journal of the Multinational Association of Supportive Care in Cancer. Feb 2015; 23 (2): 403-409.
[2] Clemence BJ, Maneval RE. Risk factors associated with catheter-related upper extremity deep vein thrombosis in patients with peripherally inserted central venous catheters: literature review: part 1. Journal of infusion nursing: the official publication of the Infusion Nurses Society. May-Jun 2014; 37 (3): 187-196.
[3] Bertoglio S, Faccini B, Lalli L, Cafiero F, Bruzzi P. Peripherally inserted central catheters (PICCs) in cancer patients under chemotherapy: A prospective study on the incidence of complications and overall failures. Journal of surgical oncology. May 2016; 113 (6): 708-714.
[4] Franklin I, Gilmore C. Placement of a peripherally inserted central catheter into the azygous vein. Journal of medical radiation sciences. Jun 2015; 62 (2): 160-162.
[5] Wang W, Zhao C, Ji Q, Liu Y, Shen G, Wei L. Prevention of peripherally inserted central line-associated blood stream infections in very low-birth-weight infants by using a central line bundle guideline with a standard checklist: a case control study. BMC pediatrics. Jun 18 2015; 15: 69.
[6] Organization WH. Cancer. Available at: https://www.who.int/health-topics/cancer#tab=tab_1.
[7] Dutia M, White RH, Wun T. Risk assessment models for cancer-associated venous thromboembolism. Cancer. Jul 15 2012; 118 (14): 3468-3476.
[8] Saber W, Moua T, Williams EC, et al. Risk factors for catheter-related thrombosis (CRT) in cancer patients: a patient-level data (IPD) meta-analysis of clinical trials and prospective studies. Journal of thrombosis and haemostasis: JTH. Feb 2011; 9 (2): 312-319.
[9] Yap YS, Karapetis C, Lerose S, Iyer S, Koczwara B. Reducing the risk of peripherally inserted central catheter line complications in the oncology setting. European journal of cancer care. Sep 2006; 15 (4): 342-347.
[10] Scrivens N, Sabri E, Bredeson C, McDiarmid S. Comparison of complication rates and incidences associated with different peripherally inserted central catheters (PICC) in patients with hematological malignancies: a retrospective cohort study. Leukemia & lymphoma. Aug 7 2019: 1-9.
[11] Kang J, Chen W, Sun W, et al. Peripherally inserted central catheter-related complications in cancer patients: a prospective study of over 50, 000 catheter days. J Vasc Access. Mar 21 2017; 18 (2): 153-157.
[12] Paje D, Conlon A, Kaatz S, et al. Patterns and Predictors of Short-Term Peripherally Inserted Central Catheter Use: A Multicenter Prospective Cohort Study. Journal of hospital medicine. Feb 2018; 13 (2): 76-82.
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[14] Gardner JD, Mouton AJ. Alcohol effects on cardiac function. Comprehensive Physiology. Apr 2015; 5 (2): 791-802.
[15] Crnich CJ, Halfmann JA, Crone WC, Maki DG. The effects of prolonged ethanol exposure on the mechanical properties of polyurethane and silicone catheters used for intravascular access. Infection control and hospital epidemiology. Aug 2005; 26 (8): 708-714.
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  • APA Style

    Cao Mingkun, Yin Yuxia, Gao Wei, Feng Shengyu, Wang Dengxu, et al. (2019). Incidence and Risk Factors of Peripherally Inserted Central Catheter-related Complications in Patients with Different Disease Types. European Journal of Preventive Medicine, 7(6), 108-111. https://doi.org/10.11648/j.ejpm.20190706.13

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    ACS Style

    Cao Mingkun; Yin Yuxia; Gao Wei; Feng Shengyu; Wang Dengxu, et al. Incidence and Risk Factors of Peripherally Inserted Central Catheter-related Complications in Patients with Different Disease Types. Eur. J. Prev. Med. 2019, 7(6), 108-111. doi: 10.11648/j.ejpm.20190706.13

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    AMA Style

    Cao Mingkun, Yin Yuxia, Gao Wei, Feng Shengyu, Wang Dengxu, et al. Incidence and Risk Factors of Peripherally Inserted Central Catheter-related Complications in Patients with Different Disease Types. Eur J Prev Med. 2019;7(6):108-111. doi: 10.11648/j.ejpm.20190706.13

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  • @article{10.11648/j.ejpm.20190706.13,
      author = {Cao Mingkun and Yin Yuxia and Gao Wei and Feng Shengyu and Wang Dengxu and Wan Min and Liu Chenghu and Wang Luning and Ge Junbo and Zhang Haijun},
      title = {Incidence and Risk Factors of Peripherally Inserted Central Catheter-related Complications in Patients with Different Disease Types},
      journal = {European Journal of Preventive Medicine},
      volume = {7},
      number = {6},
      pages = {108-111},
      doi = {10.11648/j.ejpm.20190706.13},
      url = {https://doi.org/10.11648/j.ejpm.20190706.13},
      eprint = {https://download.sciencepg.com/pdf/10.11648.j.ejpm.20190706.13},
      abstract = {Background: Cancer patients or critical patients need reliable vascular access to meet the requirements of transporting therapeutic drugs or nutrients. Peripherally inserted central catheters (PICCs) are widely used in these patients, however, the incidence of PICC-related complications is high and the data on specific diseases are not yet clear. Methods: We collected geographic characteristics and insertion information of patients with lung cancer, breast cancer, digestive tract tumor and ICU status who underwent PICC during May 2017 to June 2018. Univariate and multivariate analysis were used to estimate the risk factors of PICC-related complications. Results: 634 lung cancer, 979 breast cancer, 1453 digestive tract cancer, and 374 ICU status patients were enrolled in the study with 351 (10.2%) developed complications. There was no difference in the distribution of complications among different disease types (P>0.05). Drinking (OR 2.15, 95 CI% 1.05-3.69, P=0.012) and prior surgery (OR 1.97, 95% CI 1.05-3.69, P=0.035) were risk factors of breast cancer patients. Prior surgery (OR 2.51, 95% CI 1.54-4.09, P<0.001) and site of PICC (OR 1.56, 95% CI 1.10-2.23, P=0.014) were the influenced factors of digestive tract tumor patients. Complications of ICU status patients were influenced by smoke (OR 5.83, 95% CI 1.30-26.14, P=0.021) and prior surgery (OR 3.43, 95% CI 1.44-8.13, P=0.005). Conclusion: The targeted and reasonable prevention and nursing care should be focused on by medical staff.},
     year = {2019}
    }
    

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  • TY  - JOUR
    T1  - Incidence and Risk Factors of Peripherally Inserted Central Catheter-related Complications in Patients with Different Disease Types
    AU  - Cao Mingkun
    AU  - Yin Yuxia
    AU  - Gao Wei
    AU  - Feng Shengyu
    AU  - Wang Dengxu
    AU  - Wan Min
    AU  - Liu Chenghu
    AU  - Wang Luning
    AU  - Ge Junbo
    AU  - Zhang Haijun
    Y1  - 2019/11/07
    PY  - 2019
    N1  - https://doi.org/10.11648/j.ejpm.20190706.13
    DO  - 10.11648/j.ejpm.20190706.13
    T2  - European Journal of Preventive Medicine
    JF  - European Journal of Preventive Medicine
    JO  - European Journal of Preventive Medicine
    SP  - 108
    EP  - 111
    PB  - Science Publishing Group
    SN  - 2330-8230
    UR  - https://doi.org/10.11648/j.ejpm.20190706.13
    AB  - Background: Cancer patients or critical patients need reliable vascular access to meet the requirements of transporting therapeutic drugs or nutrients. Peripherally inserted central catheters (PICCs) are widely used in these patients, however, the incidence of PICC-related complications is high and the data on specific diseases are not yet clear. Methods: We collected geographic characteristics and insertion information of patients with lung cancer, breast cancer, digestive tract tumor and ICU status who underwent PICC during May 2017 to June 2018. Univariate and multivariate analysis were used to estimate the risk factors of PICC-related complications. Results: 634 lung cancer, 979 breast cancer, 1453 digestive tract cancer, and 374 ICU status patients were enrolled in the study with 351 (10.2%) developed complications. There was no difference in the distribution of complications among different disease types (P>0.05). Drinking (OR 2.15, 95 CI% 1.05-3.69, P=0.012) and prior surgery (OR 1.97, 95% CI 1.05-3.69, P=0.035) were risk factors of breast cancer patients. Prior surgery (OR 2.51, 95% CI 1.54-4.09, P<0.001) and site of PICC (OR 1.56, 95% CI 1.10-2.23, P=0.014) were the influenced factors of digestive tract tumor patients. Complications of ICU status patients were influenced by smoke (OR 5.83, 95% CI 1.30-26.14, P=0.021) and prior surgery (OR 3.43, 95% CI 1.44-8.13, P=0.005). Conclusion: The targeted and reasonable prevention and nursing care should be focused on by medical staff.
    VL  - 7
    IS  - 6
    ER  - 

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Author Information
  • National United Engineering Laboratory for Biomedical Material Modification, Dezhou, China

  • National United Engineering Laboratory for Biomedical Material Modification, Dezhou, China; School of Materials Science and Engineering, University of Science and Technology, Beijing, China

  • PICC Clinic, Qilu Hospital of Shandong University, Jinan, China

  • National Engineering Technology Research Center for Colloidal Materials & Key Laboratory of Special Functional Aggregated Materials, Ministry of Education, School of Chemistry and Chemical Engineering, Shandong University, Jinan, China

  • National Engineering Technology Research Center for Colloidal Materials & Key Laboratory of Special Functional Aggregated Materials, Ministry of Education, School of Chemistry and Chemical Engineering, Shandong University, Jinan, China

  • Shandong Quality Inspection Center for Medical Devices, Jinan, China; Shandong Provincial Key Laboratory of Biological Evaluation of Medical Devices, Jinan, China

  • Shandong Quality Inspection Center for Medical Devices, Jinan, China; Shandong Provincial Key Laboratory of Biological Evaluation of Medical Devices, Jinan, China

  • School of Materials Science and Engineering, University of Science and Technology, Beijing, China

  • Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai, China

  • National United Engineering Laboratory for Biomedical Material Modification, Dezhou, China; Department of Vascular & Intervention, Tenth Peoples' Hospital of Tongji University, Shanghai, China

  • Section